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DPP-4 inhibition leads to decreased pancreatic inflammatory profile and increased frequency of regulatory T cells in experimental type 1 diabetes

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The anti-inflammatory effect of liraglutide is mediated by the GLP-1 receptor signaling pathway To determine whether GLP-1R was the sole target and mediator of the anti-inflammatory effects of liraglutide, we performed a functional competition assay using exendin 939, a GLP-1R competitive antagonist, in both chondrocytes and macrophages (Fig

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